That would be a personal preference. You're going to get the same "Chevy vs Ford" argument here.
I grew up in a biker family, as did my wife (which is how we met when we were kids) our fathers rode together and would never touch anything if it didn't have the Harley Davidson name on it.
Me personally, I love the look of a Harley, but I hate the ride. I currently ride a 2000 Suzuki Bandit 1200s. Great for long distance riding, and it will get out of its own way when I hit the throttle.
Si vis pacem, Para Bellum.
"If you want peace, Prepare for war"